Ugo Basile Hot/Cold Plate
This new version of the classic instrument now works with ramping temperature (increasing or decreasing) and in a wide range of temperatures (from 2°C to 66°C). With these new features scientists can perform allodynia experiments, study receptors for cold sensitivity and run “dynamic” experiments, by changing the plate at a desired rate.
Dedicated software and memory stick included
- Direct connection to a PC
- PC Interface to serial and USB ports
- Operating Temperature presettable by function keys from 4°C to 66°C
- Multifunction graphic display readout
- Memory stick provided with the standard package
The animal is placed on the surface as a foot pedal is pressed to start a clock. The observer presses the foot pedal again when the animal makes a stereotyped paw lick response to the pain. Reaction time is measured in steps of 1/10 sec. This latency is strongly affected by analgesic drugs.
The 57280 comes with foot pedal, a restraining cylinder for rats and one for mice, a manual, and a power cord.
Ugo Basile Analgesia Hot Plate
The Conventional Hot Plate can carry out a rapid precise screening of narcotic type analgesic drugs (morphine, codeine, etc.) according to the well known method devised by N. B. Eddy and D. Leinnack which now is called the Hot Plate test.
Ugo Basile, Innovative Cold Plate
Recent research has provided information demonstrating that receptors respond differently to “cold” pain compared to “hot” pain. These novel receptors release chemicals in response to cold stimulation only. These neurons are present in both the central and peripheral nervous system. The new Hot/Cold plate provides a greater range of temperatures in order to determine pain responses to either hot or cold. Cold plate testing could be useful in studying unique and novel responses by receptors in both mice and rats.
The temperature of the plate can be set in the continuous range from 4°C to 66°C.
Both the control and the power supply of this instrument are flexible and respectively powerful enough to enable the researcher to connect an “auxillary” conventional Hot Plate with the same operation features of the complete Hot Plate.